Welcome
Global Substance Safety is a collaborative project of The Duchy of Waite and Obsidian Crown Holdings, providing evidence-based harm reduction information, emergency protocols, and substance safety resources.
Our mission is to provide accessible, accurate information to help individuals make informed decisions about substance use and stay safe.
Emergency Resources
🚨 In an Emergency?
Call 911 (USA) or your local emergency number immediately
Poison Control (USA): 1-800-222-1222
If you or someone else is experiencing an overdose or medical emergency, seek help immediately. Never hesitate to call 911 — emergency responders are there to help.
See the "Emergency Poison Control Contacts Worldwide" guide for international emergency resources.
Knowledge Base
Our comprehensive guides cover substance information, harm reduction strategies, emergency protocols, and support resources.
Emergency First Aid
Quick reference for immediate medical response and emergency protocols
EmergencyPoison Control Worldwide
Global emergency contact numbers and resources for overdose and poisoning
EmergencyUnknown Substance Response
What to do when encountering an unknown substance
EmergencyDrug Checking & Safer Use
Information about testing substances and reducing harm
Harm ReductionNaloxone & Testing Directory
Global directory of free naloxone and drug checking services
ResourcesHarm Reduction Resources
Comprehensive directory of addiction support and harm reduction services
ResourcesOpioids & Synthetic Opioids
Information about opioid substances, effects, and risks
SubstancesCNS Stimulants
Guide to stimulant substances and their effects
SubstancesDepressants & Sedatives
Information about depressant and sedative substances
SubstancesHallucinogens & Psychedelics
Guide to hallucinogenic and psychedelic substances
SubstancesDissociatives
Information about dissociative drugs and effects
SubstancesEntactogens & Novel Tryptamines
Guide to MDMA-like and research chemical substances
SubstancesCannabis & THC
Comprehensive guide to cannabis and THC products
SubstancesSynthetic Cannabinoids & Inhalants
Information about synthetic cannabinoids and inhalant substances
SubstancesNicotine & Caffeine
Guide to commonly used stimulants
SubstancesPerformance-Enhancing Drugs
Information about steroids and image-enhancing drugs
SubstancesPolysubstance Use & Interactions
Guide to substance interactions and combined use risks
SafetyMedication Poisonings & Antidotes
Information about common medication overdoses and treatments
MedicalAddiction Treatment & Recovery
Resources and information for addiction treatment and recovery
SupportDrug Testing & Adulterants
Information about testing supplies and substance adulterants
Harm ReductionAlpha Guide: Substance Abuse Reference
Comprehensive reference guide for substance abuse information
ReferenceWhat NOT to Do
Critical safety information about dangerous practices and mistakes
Safety